肠癌模型动物诱导剂

来源：作者：人气：-发表时间：2014-08-08 16:34:00【大中小】

诱发性肿瘤动物模型制作方法简便，重复性好，可以在较短时间内大量复制，而且基本模拟了癌变的过程，因此在实验中应用较广。诱发性大肠癌模型有较长的历史，目前建立大肠癌诱发模型用较多的试剂是二甲基肼(DMH)和氧化偶氮甲烷(AOM)，甲基硝基亚硝基胍(MNNG)也是得到广泛应用的一种致癌物。

氧化偶氮甲烷（Azoxymethane）是一种对大鼠和小鼠具有强力诱发大肠癌作用的物质，用于氧化偶氮甲烷诱导致畸预防性治疗的有效性评估研究。氧化偶氮甲烷也用于确认某些啮齿动物模型所使用的特殊食物，例如难消化糖，红肉和绿茶的化学预防性能。这些啮齿动物模型可以帮助鉴别可预防人类大肠癌可能的手段。

性能
氧化偶氮甲烷（Azoxymethane）
细胞生物学用 100mg
C2H6N2O=74.08
[CAS No.] 25843-45-2
含量（cGC）：98.2%

1,2-二甲基肼二盐酸盐
C2H10Cl2N2 = 133.02
[CAS No.] 306-37-6
CAS： 306-37-6

1-甲基-3-硝基-1-亚硝基胍
C2H5N5O3 = 147.09
[CAS No.] 70-25-7

相关产品

厂商货号	品牌	品名(中文)	CAS	纯度及级别	包装
011-20171	WAKO	氧化偶氮甲烷 AZOXYMETHANE	25843-45-2	细胞生物学用	100mg
0520606401	MP	二甲基肼二盐酸盐 N,N'-DIMETHYLHYDRAZINE di HCl (SYM)	306-37-6		1g
D161802-10g	Sigma	1,2-二甲基肼二盐酸盐 N,N'-Dimethylhydrazine dihydrochloride	306-37-6	98%	10g
138-14901	WAKO	1-甲基-3-硝基-1-亚硝基胍 1-METHYL-3-NITRO-1-NITROSUGUANIDINE	70-25-7		5g

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