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领军人物Nature发文：“蛋白质三明治”可能改变癌症药物的发现 [行业新闻]

: 由Alessio Ciulli教授领导的大学靶向蛋白质降解中心(CeTPD)的一个研究小组，与维也纳奥地利科学院分子医学研究中心(CEMM)的Georg Winter博士的研究小组合作，已经定义了一种新的所谓的“分子内二价胶”，它可以结合蛋白质-对细胞至关重要，使我们的身体正常运作-否则就会分开。[查看]; http://www.cxbio.com/Article/20240227_industrialnews_1.html

《Science》突破性新抗生素，遏制耐药细菌 [行业新闻]

: 来自伊利诺伊大学芝加哥分校和哈佛大学的科学家们已经开发出一种新的抗生素，cresomycin，作为对抗耐药细菌的潜在工具。这一成就源于对抗生素如何与细菌核糖体相互作用以及克服细菌防御的策略(如核糖体修饰)的研究。[查看]; http://www.cxbio.com/Article/sciencetpxxksseznyxj_1.html

mESF基础培养基/mESF添加物 [生命科学]

: mESF基础培养基/mESF添加物, 是用于小鼠ES细胞培养的无血清培养基。只需在基础培养基中添加mESF 添加物和LIF后即可进行小鼠ES细胞培养。使用时无需添加 FBS 或血清代替品，同时无需使用饲养层细胞。[查看]; http://www.cxbio.com/Article/mESF_1.html

SmartEnzymes(TM) OglyZOR(R)内切糖苷酶 [生命科学]

: OglyZOR内切糖苷酶（O-糖苷酶）特异性水解天然糖蛋白上核心1的O-聚糖，并在一定程度上水解核心3二糖。与市场上其他类似的酶相比，新颖的OglyZOR酶技术高效且易于使用。[查看]; http://www.cxbio.com/Article/OglyZOR_1.html

SmartEnzymes(TM) SmartEnzymes(TM) [生命科学]

: GingisKHAN（Kgp）是一种半胱氨酸蛋白酶，可在铰链上方的特定位点消化人IgG1。该酶仅需温和的还原条件，在含有2 mM半胱氨酸的中性pH值条件下进行反应。[查看]; http://www.cxbio.com/Article/GingisKHAN_1.html

CHO 宿主细胞蛋白残留检测试剂盒 [生命科学]

: 用于重组表达的 CHO（Chinese Hamster Ovary）宿主细胞分泌的宿主细胞蛋白（Host Cell Protein, HCP）很可能给生物制品造成污染。若药物研发早期不能充分去除污染物，则可能导致药物疗效降低或引起免疫反应。该试剂盒可高灵敏度地定量检测生物工程制药中宿主细胞蛋白的残留情况，优化工艺流程，确保生物制品的安全性。[查看]; http://www.cxbio.com/Article/CHOHost_1.html

Nature子刊：开创性的将化学探针引入活细胞，靶向红斑狼疮 [行业新闻]

: 来自Scripps Research的科学家们已经开发出一种小分子，可以阻断与自身免疫性疾病(包括系统性红斑狼疮(SLE)和克罗恩病)相关的蛋白质的活性。这种被称为SLC15A4的蛋白质一直被认为是“不可药物的”，因为大多数研究人员一直在努力分离这种蛋白质，确定它的结构，甚至确定它在免疫细胞中的确切功能——直到现在。[查看]; http://www.cxbio.com/Article/20240119_industrialnews_1.html

PNAS：一种新的检测方法有望早期发现帕金森病 [行业新闻]

: 布里格姆妇女医院的研究人员，麻省总医院布里格姆的创始成员，和哈佛大学Wyss生物启发工程研究所开发了一种分子分析平台，他们成功地应用于患者样本，以检测和量化单个synuclein原纤维，synuclein的致病聚集体是PD和其他神经退行性疾病的标志，被称为synucleinopathies。他们的研究结果发表在《美国科学院院刊》上。[查看]; http://www.cxbio.com/Article/pnasyzxdjcffywzqfxpj_1.html

残留DNA提取&检测系列 [生命科学]

: 在生物制药的生产过程中，宿主细胞携带的残留DNA可能会带来致癌性、传染性和免疫调控风险。因此需要对生产过程来源的杂质进行管理。针对提取/纯化残留DNA，FUJIFILM Wako可提供符合中国药典标准的的残留DNA提取试剂盒（碘化钠法）；此外，针对残留DNA定量检测，FUJIFILM Wako可提供定量检测CHO细胞残留DNA的qPCR试剂盒——QCdetect? Residual DNA Detection Kit for CHO cells。[查看]; http://www.cxbio.com/Article/QCdetect_1.html

SmartEnzymes(TM) OpeRATOR(R) [生命科学]

: OpeRATOR(R)?是一种 O-蛋白酶，所消化的O-糖基化蛋白在S/T糖基化位点的N端存在黏蛋白型O-糖基化。OpeRATOR要发挥酶促活性需要O-聚糖的存在。[查看]; http://www.cxbio.com/Article/OpeRATOR_1.html

Nature令人着迷的新发现：DNA复制时序 [行业新闻]

: 复制遗传信息的复杂过程被称为DNA复制，是生命从一个细胞传递到另一个细胞、从一个生物体传递到另一个生物体的核心。这不仅仅是简单的复制遗传信息，还是一个精心安排的分子事件序列，必须在正确的时间发生。来自慕尼黑亥姆霍兹大学的Maria-Elena Torres-Padilla教授研究组最近发现了这个过程的一个迷人之处，即“复制时序”(RT，replication timing)，以及生命开始时这一过程的特殊性。新的研究结果发表在《自然》杂志上。[查看]; http://www.cxbio.com/Article/naturelrzmdxfxdnafzs_1.html

Cell找到了糖尿病的新病因！这种酶能阻止体内产生胰岛素 [行业新闻]

: 凯斯西储大学（Case Western Reserve University）的研究人员发现了一种能阻止体内产生胰岛素的酶，这一发现可能为治疗糖尿病提供一个新的靶点。[查看]; http://www.cxbio.com/Article/20231212_industrialnews_1.html

人ES/ips 类器官培养 - Y27632，你选对了吗 [生命科学]

: Y-27632是一种Rho相关蛋白激酶p160ROCK的小分子抑制剂，对于p160ROCK的Ki值为140 nM，比对其他激酶，包括PKC、cAMP依赖性蛋白激酶，MLCK和PAK，作用强200倍。[查看]; http://www.cxbio.com/Article/y27632nxd_1.html

猪体外受精卵（胚胎）制备培养基系列 [生命科学]

: 日本IFP（Research Institute for the Functional Peptides）成立于1990年，致力于开发和生产动物体外受精用培养基。[查看]; http://www.cxbio.com/Article/porcine_oocyte_1.html

CiMS(TM) 人间充质干细胞用无血清培养基 [生命科学]

: CiMS(TM) 人间充质干细胞用无血清培养基，无需对培养板进行包被处理，是可用于人间充质干细胞（human Mesenchymal Stem Cells：hMSC）的无血清培养基。和添加剂配合使用，可进行长期传代培养，并提高增殖能力。[查看]; http://www.cxbio.com/Article/CiMS_1.html

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: Gerber Test Sulphuric Acid FMT d. 1.815-1.825

: Gerber Test Sulphuric Acid FMT d. 1.815-1.825

: DE-71 ( 五溴联苯醚)GreatLakes，50ug/mL 于异辛烷

: DE-79 ( 八溴联苯醚)GreatLakes，50ug/mL 于异辛烷

: Ion Chromatography Cation Standard Magnesium 1mg/ml (1000ppm)

: Magnesium Chloride StoCk Solution

: Magnesium Standard in Extracting Reagent

: Manganese Standard in Extracting Reagent

: 8 Phthalates Mixture Standard Solution (each 100ug/ml Hexane Solution)

: DCAA Methyl Ester

: ERK phospho-T202/Y204 kit - 500 tests

: Advanced ERK phospho-T202 /Y204 kit - 1 x 96 tests

: 3,5-二氯-2-羟基苯磺酸钠|54970-72-8|DHBS|Sodium 3,5-chloro-6-hydroxybenzenesulfonate

: Chromogenic Substrate for Lipase, 1,2-O-Dilauryl-rac-glycero-3-glutaric acid- (6'-methylresorufin) ester

: α-Ketoglutarate (2-Oxoglutarate) for potassium test,free acid

: Phosphoenolpyruvate (PEP), for potassium test tri(cyclohexylammonium) salt

: Taurodesoxycholat,sodium salt,ionic detergent

: Polidocanol (Thesit), Dodecylpolyethyleneglycolether

: Cholesterol esterase

: Cholesterol esterase

: Cholesterol esterase

: Cholesterol esterase

: Cholesterol Esterase

: Cholesterol Esterase

: Glycerophosphorylcholine Phosphodiesterase

: Adenosine Deaminase,from calf intestine, suspension

: Cholesterol Esterase,from Pseudomonas species, lyophilizate

: Cholesterol Esterase, chemically modified,from Pseudomonas species, lyophilizate

: Cholesterol Esterase,from Pseudomonas species, solution

: Cholesterol Esterase, from Candida cylindracea, lyophilizate

: Cholesterol Esterase, from Candida cylindracea, solution

: Galactose 1-Dehydrogenase,from Pseudomonas fluorescens, suspension

: Glucose-6-phosphate Dehydrogenase (G6P-DH),rom Leuconostoc mesenteroides, expressed in E. coli,lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH), chemically modified,from Leuconostoc mesenteroides, expressed in E. coli,lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, expressed in E. coli,solution

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, expressed in E. coli,reduced phosphate, lyophilizate

: Glucose-6-phosphate Dehydrogenase(G6P-DH),from Leuconostoc mesenteroides, suspension

: Lipoprotein Lipase,from Pseudomonas species, lyophilizate

: Lipoprotein Lipase, chemically modified,from Pseudomonas species, lyophilizate

: N-Methylhydantoinase (ATP-hydrolyzing),from Arthrobacter species, expressed in E. coli, lyophilizate

: Nitrate Reductase,from Aspergillus species, lyophilizate

: 6-Phosphogluconolactonase,from Leuconostoc mesenteroides, lyophilizate

: Liberase T-Flex, Research Grade,sterile filtered, lyophilizate

: Carboxypeptidase B, recombinant,from rat pancreas, expressed in Pichia pastoris, solution

: Endoproteinase Lys-C,from Lysobacter enzymogenes, lyophilizate

: Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate

: Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution

: Pronase,from Streptomyces griseus, lyophilizate

: Trypsin, recombinant,from porcine pancreas, expressed in Pichia pastoris

: Cholesterol esterase (CHE-XE)

: Cholesterol dehydrogenase

: Cholesterol esterase Type I

: Cholesterol Esterase1041

: Cholesterol Esterase Amano2

: Cholesterol Esterase Amano 3

: Cholesterol Dehydrogenase Amano 5

: 3,5-二氯-2-羟基苯磺酸钠 | Sodium 3,5-chloro-6-hydroxybenzenesulfonate | 54970-72-8

: 异硫氰酸荧光素酯, 5-FITC 5-Isothiocyanato fluorescein, CAS号 3326-32-7

: 荧光胺, Fluorescamine, CAS号 38183-12-9

: Cholesterol oxidase

: Cholesterol oxidase

: Cholesterol oxidase

: Putrescine oxidase

: Cholesterol Oxidase

: Cholesterol Oxidase

: Ascorbate Oxidase,from Cucurbita species, lyophilizate

: Ascorbate Oxidase, chemically modified,from Cucurbita species, poor of Aspartate aminotranferase(AST/GOT), lyophilizate

: Ascorbate Oxidase, chemically modified from Cucurbita species, lyophilizate

: Cholesterol Oxidase,from Brevibacterium species, expressed in E.coli, lyophilizate

: Cholesterol Oxidase,from Nocardia erythropolis, lyophilizate

: Cholesterol Oxidase,from Nocardia erythropolis, solution

: Cholesterol Oxidase,from Streptomyces species, lyophilizate

: Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate

: Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate

: Lactate 2-Monooxygenase (Lactateoxidase),from Pediococcus species, lyophilizate

: Cholesterol oxidase (CHO-CE)

: Cholesterol Oxidase (CHO-PEWL)

: Cholesterol oxidase (CHO-BS)

: Recombinant Cholesterol Oxidase

: Cholesterol Oxidase Amano 6E

: 抗蚜威-desmethyl-formamido

: 抗蚜威-desamido，10ng/ul 于乙腈

: 抗蚜威-desamido-desmethyl，10ng/ul 于乙腈

: Es-生物烯丙菊酯

: 氟虫腈-des F3，100ng/ul 于乙腈

: 苯嗪草酮-desamino

: 嗪草酮-desamino

: 嗪草酮-desamino-diketo

: 丁草胺-ESA 钙盐

: 二甲草胺-ESA 钠盐

: 吡唑草胺-ethane sulfonic acid (ESA)

: 异丙甲草胺-ethane sulfonic acid (ESA)

: 扑草胺-ethane sulfonic acid (ESA) sodium salt

: Presep(R) Diatomaceous Earth, Granular (Column Volume 15mL)

: Presep(R)-Agri

: Presep(R) Diatomaceous Earth, Granular (Column Volume 6ml)

: Presep(R)-C Agri (Short)

: USP Solution Bromocresol Green TS Conforms to USP 34

: USP Solution Bromocresol Green TS Conforms to USP 34

: USP Solution Bromocresol Purple TS Conforms to USP 34

: USP Solution Bromocresol Purple TS Conforms to USP 34

: USP Solution Dichlorofluorescein TS Conforms to USP 34

: USP Solution Dichlorofluorescein TS Conforms to USP 34

: USP Solution Resorcinol TS Conforms to USP 34

: USP Solution Resorcinol TS Conforms to USP 34

: European Pharmacopoeia Reagent Bromocresol green Solution

: European Pharmacopoeia Reagent Bromocresol Green - Methyl Red Mixed Indicator

: European Pharmacopoeia Reagent Indicator Solution Bromocresol Purple 0.04%

: European Pharmacopoeia Reagent Bromocresol Green - Methyl Red Mixed Indicator

: European Pharmacopoeia Reagent Bromocresol Green - Methyl Red Mixed Indicator

: European Pharmacopoeia Reagent Concentrate to make Magnesium standard sol (100ppm Mg)

: Anhydroecgonine methyl ester,1.0mg/mL 于乙腈

: Acesulfame potassium impurity B

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